The primary purpose of this book is to provide a comprehensive understanding of patient decontamination in healthcare settings. It aims to explore the principles, practices, and protocols involved in decontaminating patients who have been exposed to hazardous substances or infectious agents. This book serves as an educational resource for healthcare professionals, emergency responders, and students seeking knowledge about patient decontamination. It offers a structured approach to learning about decontamination procedures, from basic principles to advanced techniques. This book advocates for standardized decontamination protocols based on evidence-based practices and regulatory requirements, thereby promoting uniformity across healthcare settings. Another objective of the book is to enhance preparedness and response capabilities for decontamination incidents. It equips readers with the knowledge and skills necessary to respond promptly and effectively to contamination emergencies, whether they occur in hospitals, clinics, or other healthcare facilities.